Yes have had a queen fly away. If you watch her most times she will circle and come right back. Looked for a queen one day for about an hour, was putting the hive back together as I had given up on finding her, lo and behold she was walking around on my pants leg. Wife found one on the ground and luckily I did not step on her. Early released a bought queen from Texas, watched her fly back home to Texas.
You never can be sure what they are going to do.
If you see her fly off usually just stand still and she will circle and come back, using you for an orientation point.