Think of a nuc as FRAMES of bees.. if you have a full double nuc it equals ten frames (provided they are 5 frame nucs) and you would use the same amount as you do for a ten frame single.
To be perfectly Honest, I do not disparage between five and ten frames if the five frame nuc is full. I worry that the small amount of OA is insufficient to penetrate the entire nuc. But I do increase the amount with each additional box. I have to divide the amount by three since I use mediums.